S1 Diagram of network and forces acting on nodes
S2 Cross-section of network showing links around bead (the bead would be in the lower left—not plotted so as not to obscure the links)
S3 Basic form of the main program loop
S4 Interactive 3D reconstructions of in silico shells from unconstrained (top) and constrained (bottom) beads showing linear crack or bi-lobed structure
S5 2D projections (left) and corresponding interactive 3D reconstructions (right) of constrained beads (5um spacers) showing smooth opening of shell without bi-lobed structure
S6 2D projections (left) and corresponding interactive 3D reconstructions (right) of unconstrained beads (15um spacers) showing bi- and tri-lobed structure
S7 Interactive 3D view of in silico network trajectory relative to bead during smooth motion
S8 Interactive 3D view of in silico network trajectory relative to half-coated capsule during smooth motion
S9 2D projections (left) and corresponding interactive 3D reconstructions (right) of shells and tails from unconstrained ellipsoidal beads showing sideways symmetry breaking and motility
S10 Effect of varying RADIUS
S11 Effect of varying P_XLINK
S12 Effect of varying P_NUC
S13 Effect of varying LINK_BREAKAGE_FORCE
S14 Effect of varying LINK_FORCE
S15 Effect of varying NODE_REPULSIVE_MAG
S16 Effect of varying NUC_LINK_FORCE
S17 Effect of varying NUC_LINK_BREAKAGE_DIST
S18 Effect of varying NUCLEATOR_INERTIA
S19 Effect of varying FORCE_SCALE_FACT
S20 Effect of varying P_XLINK with no bead-network friction
S21 Detailed program flow